Today, we are already at a turning point in our ability to 3D
“bioprint” organ tissues, a process that involves depositing a “bio-ink” made
of cells precisely in layers, resulting in a functional living human tissue for
use in the lab. These tissues should be better predictors of drug function than
animal models in many cases. In the long-term, this has the potential to pave
the way to “printing” human organs, such as kidneys, livers and hearts.
Achieving such an outcome would be truly remarkable. Despite advances in
medicine and increased awareness of organ donation, the gap between supply and
demand of organs continues to widen. Without an accurate digital model
of your target organ, bioprinters have nothing to guide them. This necessity
gets more evident when attempting to grow a large solid, organ with its
complicated architecture involving blood vessels, different cell types and
geometrical quirks.
Though printable organs won’t come easily, there is reason for optimism:
i) Regenerative medicine isn’t brand
new, ii) Costs are decreasing,
Research is focused on the whole body, iii) 3D printed tissues and organs show
promise in the lab. By 2020, our goal is to have the
technology be broadly used by pharmaceutical companies, resulting in the
identification of safer and better drug candidates and fewer failures in
clinical trials.
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